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Clinical trials have highlighted challenges in achieving therapeutically relevant EGCG concentrations, with conventional oral administration strategies often resulting in low systemic concentrations

Biochem Pharmacol 76:15441553

This creates a challenging bottleneck for formulators who need to deliver a functional dose to achieve the desired output

Exploratory analysis of adjuvant chemotherapy benefits after preoperative chemoradiotherapy and radical resection for rectal cancer

Preoperative bevacizumab does not significantly increase postoperative complication rates in patients undergoing hepatic surgery for colorectal cancer liver metastases