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Route of administration also affects observed half-life

It will then allow oxygen to circulate through tissues with greater efficiency

According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

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The magic behind semaglutide is that it offers systemic metabolic support, satiety control, slowed digestion, and blood sugar regulation with once-weekly dosing thanks to its long half-life