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3.2 Primary Mechanism: Actin Sequestration The primary and most well-characterized function of Thymosin Beta-4 is its role as a G-actin (globular actin) sequestering protein

In this regard, it is interesting that IgG antibodies that show similar FcRn binding properties can have variable plasma half-lives due to differences in biophysical properties, such as pI and net charge, which affect cellular handling 83,84,85,86,87

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A Practical Approach for the Management of the Mixed Opioid Agonist-Antagonist Buprenorphine During Acute Pain and Surgery