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Docosahexaenoic acid (DHA), a typical -3 polyunsaturated FA, is highly enriched in oils from deep-sea fish and marine microalgae and promotes adipocyte apoptosis to combat obesity in mammals and fish (Tatsumi et al., 2022)

These radicals initiate lipid peroxidation of PUFAs within membrane phospholipids, leading to membrane disruption and ferroptosis ( + functions as a cofactor for multiple metabolic enzymesincluding LOXs and PDH1enhancing their activity and further stimulating ROS production ( + influx, elevates ROS levels, and increases cellular sensitivity to ferroptosis

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The fruit is high in calories, sugar, and saturated fats, which can negatively affect liver health if eaten in large quantities

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