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These effects suggest two distinct influences of curcumin on the microbiota: firstly, curcumin modulates microbiota composition, and secondly, microbiota causes biotransformation of curcumin (Scazzocchio et al., 2020)

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It is possible that the low levels of RNF4 protein present in HaCaT cells may be less available, as it may be largely associated with nuclear PML bodies or bound to SUMOylated proteins

Targeting the tumor vasculature has been recognized as an effective strategy to disrupt solid tumors

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