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Researchers found that the participants had improved lean body mass and muscle strength, as well as decreased fat mass when compared to the placebo group

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Blood specimens were obtained for the evaluation of lipid profiles and MDA quantification, while aortic tissues were scrutinized for the presence of intimal lesions

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By late 2025, over 40 PROTAC candidates had entered clinical evaluation across oncology, autoimmune disorders, and neurodegeneration (Table 1), targeting proteins including AR, ER, BTK, and IRAK4 [57, 58]