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AXL/MERTK inhibitor ONO-7475 potently synergizes with BCL2 inhibitor ABT-199, overcomes ABT-199 resistance mechanisms, and kills FLT3 ITD AML cells

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Interestingly in the absence of doxycycline, oxidative stress resistance of the wild-type reference isolate was apparently higher than the one of the TetOFF strain, although steady state transcript levels had been monitored to be elevated for the latter

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Gordon was one of the authors, specifically emphasized the importance of obtaining baseline x-rays