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Description

Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway

Transaconitate from the tricarboxylic acid cycle was elevated in ME/CFS along with essential aromatic amino acids, lysine, purine, pyrimidine and microbiome metabolites

10.1186/s13023-016-0426-y 36 FanL.DuP.LiY.ChenX.LiuF.LiuY.et al (2024)

First, multimodal assessment systems integrating mtDNA mutation profiling, transcriptomics, and proteomics were established, as demonstrated in early diagnostic models for lung adenocarcinoma and prognostic NMG models for pancreatic cancer