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Lastly, Brachyury expression - often considered a NC marker and required for the differentiation of mesoderm into notochord [3] - was not detected in the human adult NP, which may argue against the hypothesis that both NC and CLCs are derived from the notochord [73]

KPV exerts its anti-inflammatory function inside colonic cells, which inactivates inflammatory pathways by reducing pro-inflammatory cytokine genetic expression

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