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Chan KL, Puts NA, Schr M, Barker PB, Edden RA

Zhang X, Liu W, Li Y, Li X, Quan M, Mohan R , Anand A, Sahoo N, Gillin M, Zhu XR

Amino Acids 32, 235242

In an experiment in which a stable DHODH knockout human corneal epithelial cell (HCEC) line was established, the balance of expression between DHODH and GPX4 closely regulated cellular ferroptosis homeostasis (56)

The secondary metabolites produced may be natural like phytohormones or any nutrients or alkaloids, terpenes, quinines, benzopyranones, chinones, phenolic acids, terpenoids, steroids, flavonoids, hydrocarbons, etc., in response to stressed condition (Tiwari, 2015