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However, topical formulations have also shown low bioavailability, mainly due to the low efficiency of transdermal administration and automatic photodegradation of EGCG [28]

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In related research, murine models with elevated lipid serum profiles showcased an increased secretion of IL-6 from CD1b+ dendritic cells, suggesting its role in modulating T cell orientation and heightening IL-17A output by HJ1 T cells (64)

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Nevertheless, the ever growing list of publications regarding this topic validates aaRSs as an extremely interesting target for drug design