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Moreover, significant differences were observed in the required times between the phase I and phase III studies, and a difference in those between phase I and phase II studies was nearly significant ( p = 0.0563)

The anti-obesity effect of the combined treatment amylin/PYY3-36 was evaluated in an animal study, given that they both may have the potential for short-term signals of meal termination with anorexigenic and weight-reducing effects (201, 202)