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Description

The transcription factor, nuclear factor erythroid 2-like 2 (NRF2), governs the expression of antioxidant response elements, including GPX4 (70)

& Duvall, C

Consequently, this mouse model of mild glutamatergic hyperfunction has been used in a series of proof of principle studies that investigated the functional role of glutamate in animal models of neurodegenerative diseases