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NRF2 has since been described as the principal regulator of antioxidant response in cells

showed that MET-treated mice had similar lung Mtb CFU compared to control mice, and the percentage of mice with Mtb culture relapse was similar between the two groups (166)

Meyer, M., Dimroth, P

Mechanistically, the blockade of CCL5 increases the production of HGF from reparative macrophages via the CC motif chemokine receptor CCR1- and CCR5mediated forkhead box protein O3 (FOXO3) pathways