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4 It is for the same reason that when warfarin is initiated, its antithrombotic effect is not realized until at least 5 days of treatment has elapsed

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To aid in this increased speed of the fibroblasts, focal adhesion kinase is significantly elevated in fibrotic tissue, and targeting the activity of focal adhesion kinase has been shown to reduce fibrosis [115,116]

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Briefly, cells were harvested and homogenized in ice-cold homogenization buffer, followed by centrifugation at 1,000 g for 10 min to remove nuclei and unbroken cells