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Bernhardt ML, Kong BY, Kim AM, OHalloran TV, Woodruff TK (2012) A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes

Wolfram syndrome-1 (WS1) is primarily caused by mutations in the WFS1 gene encoding the ER-resident wolframin protein, presenting with diabetes mellitus, optic atrophy, neurological deficits, and hearing impairment [173]