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To date, we have identified 25 genetically encoded selenoproteins in human, including glutathione peroxidase (GPx), thioredoxin reductase (TXNRD), and iodothyronine deiodinases (DIOs), which have a wide range of functions, from anti-inflammatory and antioxidant activities to thyroid hormone metabolism

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Lin Y-K, Liang C-H, Lin Y-H, Lin T-W, Vazquez JJ, van Campen A, et al

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elegans lamin a gene), which also exhibit a short life span and altered nuclear architecture (Bank and Gruenbaum, Lipase Action and a Link to Autophagy Two recent studies suggest that lipid-remodeling enzymes other than the desaturases can also influence longevity, namely the lipases