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doi: 10.1186/s40001-025-03124-y

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In conclusion, this study elucidates the significant role of DP in alleviating sciatica pain by protein microarray and experimental validation, The potential mechanism involves downregulating the expression of key inflammatory mediators IL-6 and CINC-3, thereby inhibiting neutrophil migration and promoting neuroprotection through the upregulation of CNTF(Fig

The administration of a synthetic peptide (FOXO4-DRI = FOXO4-D-Retro-Inverso) to avoid the interaction between FOXO4 and p53 leads to a decrease of irradiated-induced senescent fibroblasts viability

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