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Description

Aging defect at the QO site of complex III augments oxyradical production in rat heart interfibrillar mitochondria

found that 7-isopentenoxycoumarin significantly induced melanogenesis at a dose of 40 m, with the highest induction of melanin at 72 h, and excitingly the induction was 6-fold greater than that of the control group, and the mechanism of action was to increase melanogenesis by elevating MITF and its downstream genes tyrosinases, TRP-1 and Trp-2