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The group used immunohistochemistry to assess the effect of either histamine deficiency ( Hdc KO mouse model) or histamine stimulation in wild type mice on microglia

Each group was supplied with drinking water (DW) from a separate container

This phase relies heavily on the Cytochrome P450 (CYP450) superfamily of enzymes, which are heme-containing monooxygenases located primarily in the smooth endoplasmic reticulum of hepatocytes (liver cells)

doi: 10.1038/s41419-022-05225-6 42 WoelkCHBeliakova-BethellNGoicoecheaMZhaoYDuPRoughtSEet al

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