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This effect results from Depo-Proveras suppression of ovulation combined with thinning of the endometrial lining , making bleeding less likely to occur

Vaccines 20 , 15491560 (2021)

In the trial, palovarotene reduced the annualized heterotrophic ossification by 54% compared with standard of care without introducing new safety signals

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Clinical signs are indistinct and include lethargy, depression, ataxia, anorexia and intermittent vomiting, and in severe cases, can induce neurological disease and blindness in cats