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11 , CD002779

In the classical pathway, NF-B/Rel binds to and is inhibited by IB 119

doi: 10.1002/adhm.202304522 185

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Ser/gly synthesis dependence led to an enhanced synthesis of nucleotides in 2012.2 GBM cells, as well as in 1919 GBM isogenic models with overexpression of PSPH and the PSPH V116I mutation, which explains their high sensitivity to the inhibitory effects of sertraline plus chloroquine treatment