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Briefly, TC16 cells were seeded into 24-well plates at an initial seeding density of 5 10 5 cells/well in complete DMEM medium

Patients with moderate or severe HI had increased cabergoline exposure [see CLINICAL PHARMACOLOGY ], which may increase the risk of DOSTINEX-associated adverse reactions

This NADPH stress suppresses the rate of lipogenesis and increases sensitivity to oxidative stress in mtIDH1 cells in culture 156 , despite mtIDH1 cells exhibiting increased oxPPP flux 157