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With respect to cell death, induction of p21 FL modestly delayed the onset of erastin2-induced death alone, and to a greater extent when combined with nutlin-3, consistent with an independent requirement for both p53 and p21 in the suppression of ferroptosis (Fig 2F)

While this approach is appropriate for capturing early oxidative and micronutrient-related alterations associated with disease severity, it does not allow evaluation of temporal dynamics, recovery patterns, or causal relationships, which would require longitudinal follow-up

Julie K

Standard urine tests detect alcohol for 12 to 24 hours