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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B

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In this regard, it has been shown that tamoxifen, a type of selective estrogen receptor modulator (SERM) that acts as a competitive antagonist or as a partial agonist depending on the cell type, favors the repair of demyelinated lesions in the CNS by increasing the mRNA levels of myelin basic protein (MBP) and 2, 3-Cyclic nucleotide 3-phosphodiesterase (CNP), two genes highly expressed during oligodendroglial differentiation (Gonzalez et al., 2016)

Figures 1: Essential and Non-Essential Amino Acids Protein Metabolism and Synthesis in the Body Figure 2: Protein cannot be stored and is broken into amino acids for new proteins, nonessential amino acids, and nitrogen compounds