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Metabolism & Conjugation: Glutathione conjugation performed a great role in the metabolism of chlorothalonil and subsequent complex metabolic processing of these conjugates occurs in particular renal uptake and urinary excretion of thiol-derived metabolites

This activity relies to the binding of a heme, which is stabilized by hydrogen bonds when a glutathione is present in the active site (Yamada and Takusagawa, 2007

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Then, we present the genomic characterization of HGF/c-MET pathway in carcinogenesis