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This interaction increases the risk of side effects like tremors, high blood pressure, and kidney toxicity

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2025;31(6):e70016

Interestingly, oxidatively modified biomolecules can not only be counteracted by direct repair or restoration responses but also serve as signaling molecules to participate in redox regulation

This group included known fumarate-related proteins 60 such as MMS19 (a nucleotide excision repair protein) and LIN7C (lin-7 homolog C), and 21 of the 25 proteins were known exosomal components (Fig