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Guthold, R., Stevens, G

It is important to note, since Glx/tNAA indexes the cortical glutamate + glutamine pool rather than synaptic glutamate release alone, the attenuation we observed may reflect metabolic changes as well as altered neurotransmitter cycling, consistent with C-MRS evidence that prefrontal tricarboxylic (TCA)-cycle activity can fall without a corresponding change in glutamate and glutamine cycling in depression 36

Green fluorescence was examined

Animal Study Experimental design: A total number of 35 Wistar albino rats were obtained from the Animal House, Physiology department of the University of Ibadan weighing between (95-110g)

However, we could not find significant changes in GST activity when cell were treated with DEM or BSO