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Combining these strategies with immune checkpoint inhibitors and cell-based therapies, such as cancer vaccines and adoptive T-cell or NK-cell therapies, holds significant potential for overcoming immune resistance

Other symptoms may include: Clay-colored stools Nausea and vomiting Exams and Tests Tests used to detect gallstones or gallbladder inflammation include: Ultrasound, abdomen CT scan, abdomen Endoscopic retrograde cholangiopancreatography (ERCP) Gallbladder radionuclide scan Endoscopic ultrasound Magnetic resonance cholangiopancreatography (MRCP) Percutaneous transhepatic cholangiogram (PTCA) Your health care provider may order the following blood tests: Bilirubin Liver function tests Complete blood count Pancreatic enzyme (amylase or lipase) Treatment SURGERY Most of the time, surgery is not needed unless symptoms begin

The increase in neuroinflammation is mainly attributed to age-related changes in microglia [185]