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It is a heme-containing enzyme that produces O2 from H2O2 It reduces H2O2 and organic hydroperoxides using GSH and requires selenium It converts superoxide into hydrogen peroxide without cofactors It oxidizes GSSG to GSH using NAD+ Correct Answer: It reduces H2O2 and organic hydroperoxides using GSH and requires selenium Q5

Subsequently, caspase-1 is activated, which in turn cleaves Gasdermin D (GSDMD), leading to cell membrane perforation and release of interleukin-18 (IL-18) and IL-1, ultimately resulting in cell swelling and pyroptosis (Liu et al., 2024)

Chronic obstructive pulmonary disease: an emerging comorbidity in HIV-infected patients in the HAART era

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Plasma steroid concentrations in male rhesus monkeys following treatment with the P450c17 (CYP17) inhibitors VT-464 and abiraterone acetate: a comparison to human 17,20-Lyase (lyase) and combined lyase/17-hydroxylase (hydroxylase) deficiencies [abstract]