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Although resveratrol shows promising anti-cancer potential, its efficacy has been limited to tumors with direct contact, such as skin cancers or gastrointestinal tract cancers, rather than human solid tumor cells, due to its poor bioavailability [128]

BSO showed synergistic effect on the ROS production in HCT116 cells while it has practically no benefits in ROS production of SNU478 cells

Importantly, we here demonstrate that the REW substitutions strongly attenuate binding to SpA (Fig S5r, s), and accordingly, IgG1-REW could efficiently engage C1q, even in the presence of 5-molar excess of SpA, which prevented binding to WT IgG1 (Fig

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