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Patients in the treatment arm survived a median 13.3 months without disease progression, while those in the control group lived only 4.4 months without their disease advancing

and Dehay B., Alphasynuclein Spreading in Parkinson's Disease, Front Neuroanat 8 (2014): 159

Beyond the emergency room: prescribing buprenorphine with linkage to long-term care Before considering initiation of buprenorphine, emergency clinicians should be keenly aware of what resources are available for their patients for follow-up care and should adjust their prescribing practice based on said resources