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However, it is speculated that the impact of mitochondrial dysfunction on energy metabolism, calcium control, and membrane excitability can interfere with intestinal homeostasis, weaken immune responses, and cause the chronic inflammation seen in IBD (72)

10 The JNK pathway regulates cell cycle progression through multiple mechanisms

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Results Generation and screening of FGF5 KO sheep Since we have investigated the efficiency of detecting mutations by PCR sequencing (Supplementary Table S1), the blood DNA template was screened for positive individuals using PCR and DNA sequencing (Supplementary Fig