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Each experiment was replicated twice

Notably, dominant chemical markers of pravastatin treated mice are oxidized lipids (7 out of 10 species) as compared to control (3 out of 10 species)

The data indicate that altering the anatomical route and kinetics of nutrient presentation to the distal gut reinstates physiological lipid fluxes and mitigates metabolic dysregulation (7, 49)

Presumably, the combination of ROS accumulation with a COVID-19-specific hypoxia triggered a shift to anaerobic glycolysis, which is a primary factor driving immunometabolic dysfunction in CD8 lymphocytes during SARS-CoV-2 infection

Am Heart J 163(1):712 Lee BK, Schwartz BS, Stewart W, Ahn KD (1995) Provocative chelation with DMSA and EDTA: evidence for differential access to lead storage sites