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doi: 10.1186/s13072-015-0020-x 30 ReichMLiefeldTGouldJLernerJTamayoPMesirovJP

[1] [12] For most people, doses up to 2 mg (2000 micrograms) daily are unlikely to cause harm according to NHS guidance, as B12 is water-soluble and excess is typically excreted in urine

Giannoudis PV, Calori GM, Begue T, Schmidmaier G

We understand that maintaining peak cognitive function and sustained energy becomes increasingly challenging as cellular health naturally declines over time