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Such as erythropoietin or darbepoetin, used for anemia associated with chronic kidney disease or chemotherapy-induced anemia to stimulate the bone marrow to produce more red blood cells

Metformin is well absorbed orally, not metabolized, but excreted unchanged by kidney by active tubular secretion Side effect: General side effects are Nausea and vomiting, Diarrhea, metallic taste, abdominal discomfort and anorexia