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Hashimotos Thyroiditis For patients with Hashimotos thyroiditis, the KD offers a nuanced therapeutic potential that requires careful personalization

Mild HHcy is usually caused by mild impairment of the methylation pathway and is associated with folate or B12 deficiencies or the thermolability of MTHFR [2]

More help Key Event Relationship Overview The utility of AOPs for regulatory application is defined, to a large extent, by the confidence and precision with which they facilitate extrapolation of data measured at low levels of biological organisation to predicted outcomes at higher levels of organisation and the extent to which they can link biological effect measurements to their specific causes.Within the AOP framework, the predictive relationships that facilitate extrapolation are represented by the KERs

(2020) 369:m2382

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