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Lee J, Zhang LL, Wu W, Guo H, Li Y, Sukhanova M, Venkataraman G, Zhang H, Alikhan M, Lu P, Guo A, Galanina N, Andrade J, Wang M , Wang YL

The antibody-drug conjugate (ADC), which was originally developed under a partnership between Seagen and Genmab, was granted accelerated approval in September 2021 based on a 24% objective response rate seen in the Phase II innovaTV 204 trial

The FDA has approved zinc oxide (ZnO) as a safe metal oxide, which is less toxic than many other metals and exhibits low reactivity with active pharmaceutical ingredients

The catalytic cysteine is highly susceptible to oxidation and nitrosylation, leading to reversible or irreversible modifications that abolish its nucleophilic function and inactivate its enzyme activity (87, 88)

CAR-T after stem cell transplantation in B-cell lymphoproliferative disorders: are they really autologous or allogenic cell therapies