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Disulfide-containing high mobility group box-1 promotes N-Methyl-d-Aspartate receptor function and excitotoxicity by activating toll-like receptor 4-dependent signaling in hippocampal neurons

7 Conclusion and future aspect BV is a complex biological mixture containing various bioactive components, such as peptides (notably melittin and PLA2), phospholipids, proteins, amino acids, enzymes, carbohydrates, minerals, and small amounts of volatile components

The pathogenesis of HAPH involves various factors, such as vascular remodeling, endothelial dysfunction, inflammatory response, and genetic predisposition