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There is a hope that in the next future it will be achievable to block other mutation variants of KRAS other than G12C, making possible to exploit this approach also in other KRAS mutant tumors

During this conjugation process, an enzyme family called glutathione S-transferases (GSTs) catalyzes the physical attachment of the glutathione molecule directly to the toxic compound

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MSCs treatment has been demonstrated in numerous studies to effectively suppress pathogenic processes in SS and influence the SG microenvironment by replacing the fibrotic matrix (158, 160, 205208)