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exposed to cadmium (Cd 2+ ) and mercury (Hg 2+ )

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIf-mediated cell death

Supporting this concept, examining the ARCHS4 co-expression analysis further revealed a positive correlation between ATM expression and genes upregulated in response to glutamine deprivation (Fig

In contrast, Fer-1, a specific ferroptosis inhibitor, has been shown to reduce the lipid peroxidation end products, thus inhibiting cardiomyocyte death and preventing neutrophil recruitment after heart transplantation (63)

h-i , Immunoblots ( h ) and IHC ( i ) analyses of Cleaved Caspase-3 (CC3-Asp175) in small intestine crypts from control- and CysRD-fed mice, assessed both at baseline and 8 h after irradiation