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doi: 10.3389/fphar.2021.654023 103 GuoYZhangHLvZDuYLiDFangHet al

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This situation allows direct interactions between intestinal microbiota components and humoral and cellular mediators from the immune system and the CNS, triggering an immune response characterized by increased production of inflammatory mediators (Wang et al., 2022

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Another member of this family, LGP2 (Laboratory of Genetics and Physiology 2), possesses a domain structure analogous to that of RIG-I and MDA5 but has received comparatively less attention [221]

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