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This is evident from the contrasting results of metE-DNA vaccination and metE-protein-adjuvant vaccination in vivo

This was accomplished by significantly lowering the expression of the pro-apoptotic protein Bax and increasing the production of the anti-apoptotic protein Bcl-2 (Wang and Li 2021)

To the best of our knowledge, we are the first to hypothesize that DPP-4 inhibitors might emerge as a valuable asset in the alleviation of COVID-19 long-term repercussions following patients recovery, given their favorable effects in protection and tissue regeneration