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The identification of dysregulated incretin secretion and action in both obesity and diabetes led to the revolutionary discovery of incretin-based drugs, such as glucagon-like peptide 1 (GLP-1) receptor agonists (RAs) and dual glucose-dependent insulinotropic peptide (GIP)/GLP-1 RAs [24,25,26,27,28]

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Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105

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4.1.3 Fatty acid oxidation Through metabolic reprogramming, AML cells have a strong reliance on fatty acid oxidation (FAO) and fatty acid synthesis, a metabolic signature that is essential for their quick growth, energy provision, and biosynthesis

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Structure determination and refinement The X-ray diffraction data were collected at the NSLSX25 beam line at the Brookhaven National Laboratory

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doi: 10.2147/JIR.S347955 65 LiYLiXLiJ

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