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CHOP inhibits the activity of anti-apoptotic proteins Bcl-2 and Bcl-xL, disrupting the balance between apoptosis and anti-apoptosis within the cell, making it easier for the cell to undergo apoptotic outcomes (Urano et al., 2000)

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Finally, to provide a reference for further research on protection against alcoholic liver injury as well as the development of novel liver-protecting drugs and functional foods