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While the dysregulation of EAAT3 has been associated with metabolic reprogramming and the progression of various solid tumors, the precise regulatory mechanisms governing EAAT3 remain insufficiently understood

Unless otherwise specified, all reactions were performed in 20 mM Tris-HCl pH 8.0,150 mM NaCl buffer, with 25 M of freshly prepared Th-T (ThermoFisher Scientific) added to each reaction

Gives the simplified mechanism and provides the information about naturally occurring peptides containing pyroglutamate

[DOI] [PMC free article] [PubMed] [Google Scholar] 269.Petri S., Kiaei M., Damiano M., et al

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