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Importantly, monocytes possess the capability to stimulate ECs directly, which may lead to decreased occludin levels and a heightened influx of immune cells into the inflamed site [27]

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Thymosin Beta4 Induces Angiogenesis Through Notch Signaling in Endothelial Cells, Lv S, Cheng G, Zhou Y, Xu G, Molecular and Cellular Biochemistry, 2013 Sep;381(12):283290