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Folic acid alone, folic acid combined with vitamins B 12 and B 6 , and vitamins B 6 and B 12 have all been shown to reduce homocysteine concentrations

In contrast, Ginkgo biloba exerts comparatively modest direct monoaminergic effects

Finally, as with any scoping review, potential publication bias cannot be excluded, since studies with significant or positive results are more likely to be published than those with null findings