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To further our understanding of primary cilia's function in CCA, we investigated whether the loss of primary cilia affects DNA damage response (DDR) and DNA repair processes

The use of multiple analytical platforms allowed for a more holistic view of the metabolic alterations preceding GDM development

Functional performance, muscle strength, muscle power, body composition, and waist circumference were evaluated before and after the intervention, and a subset underwent muscle and adipose tissue biopsies to assess mitochondrial and lipid-metabolism markers

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