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Methods in Molecular Biology, vol 1764

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These results suggest that, following the activation of NF-B by docetaxel, apoptosis is elicited through a mitochondria-dependent pathway ( CTX is a taxane drug that can induce apoptosis or autophagy by inhibiting the phosphorylation of PI3K/Akt/mTOR and is effective in some drug-resistant tumors

Upon electrostatic interactions between the anionic mucin on the ocular surface and cationic 89WP, the 89WP-engaged conjugate adhered to the ocular surface and markedly improved drug permeation into the retina